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Fletta eftir efnisorði "Gene Expression Profiling"

Fletta eftir efnisorði "Gene Expression Profiling"

Röðun: Raða: Niðurstöður:

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    Glutamine to proline conversion is associated with response to glutaminase inhibition in breast cancer 
    Grinde, Maria T; Hilmarsdóttir, Bylgja; Tunset, Hanna Maja; Henriksen, Ida Marie; Kim, Jana; Haugen, Mads H; Rye, Morten Beck; Mælandsmo, Gunhild M; Moestue, Siver A (2019-05-14)
    INTRODUCTION: Glutaminase inhibitors target cancer cells by blocking the conversion of glutamine to glutamate, thereby potentially interfering with anaplerosis and synthesis of amino acids and glutathione. The drug CB-839 has shown promising effects ...
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    KNeMAP : A network mapping approach for knowledge-driven comparison of transcriptomic profiles 
    Pavel, Alisa; Del Giudice, Giusy; Fratello, Michele; Ghemtio, Leo; Di Lieto, Antonio; Yli-Kauhaluoma, Jari; Xhaard, Henri; Federico, Antonio; Serra, Angela; Greco, Dario (2023-06-01)
    MOTIVATION: Transcriptomic data can be used to describe the mechanism of action (MOA) of a chemical compound. However, omics data tend to be complex and prone to noise, making the comparison of different datasets challenging. Often, transcriptomic ...